Currently Recruiting Clinical Trials in New York City
 

List compiled by TMT (Taylor MicroTechnology, Inc.): Last updated: December 28, 2007.

To receive a free report on US trials of a specific disease, to add a trial to our trials listing, or to be added to our email  list, write clinicaltrialsnyc@masterdocs.com  

To search for a word (e.g., pain), click 'Edit' on the menu bar above, and then 'Find (on this Page)'. Type the search word in the dialog box and click the 'Find Next' button repeatedly to scroll through the document.

In addition to the trials listed below, a website at http://www.ifpma.org/clinicaltrials.html allows you to search for clinical trials in your own zip code (or geographically close zip codes). Go to this website, select "search ongoing trials", type 1) the name of the disease you are interested in and 2) your zip code in the "Enter search text" field (e.g., hypertension 10021). You will be shown a list of clinical trials in that disease in that zip code. You can review these trials to see if they are of interest to you. You can also use the list of doctors researching this disease as a possible source of a personal specialist for yourself.

To participate in a trial in chronic pain, go to Chronic Pain Trials.

Total Studies Listed = 976 

 

   1

 

Recruiting

 

Cardiovascular Disease Risk Factors in Chinese American Immigrants

Conditions:

 

Hypertension;   Cardiovascular Diseases;   Diabetes Mellitus;   Metabolic Syndrome X

Intervention:

 

 

 

 

 

 

 

 

 

2

 

Recruiting

 

SmartCPR Trial: An Analysis of a Waveform-Based AED Algorithm on Survival From Out-of-Hospital Ventricular Fibrillation

Conditions:

 

Ventricular Fibrillation;   Cardiac Arrest

Interventions:

 

Device: Immediate defibrillation;   Device: SmartCPR;   Other: Delayed defibrillation

 

 

 

 

 

 

 

3

 

Recruiting

 

A Study of Survivorship Service Capacities Among Health Care Agencies in New York City

Condition:

 

All Cancers

Intervention:

 

 

 

 

 

 

 

 

 

4

 

Recruiting

 

Psychosocial Support for Cancer Patients

Condition:

 

Cancer

Interventions:

 

Behavioral: Dignity Psychotherapy;   Behavioral: Supportive Psychotherapy;   Behavioral: Standard Palliative Care

 

 

 

 

 

 

 

5

 

Recruiting

 

Efficacy of Voice Treatment for Parkinson's Disease

Conditions:

 

Parkinson's Disease;   Dysphagia;   Dysarthria

Interventions:

 

Behavioral: Voice/Respiration Treatment;   Behavioral: Speech/Articulation Treatment;   Behavioral: No intervention (PD);   Behavioral: HC control

1

 

Recruiting

 

Medicinal Plant Use for Treating Inflammation Among Dominicans in New York City and the Dominican Republic

 

Condition:

 

Inflammation

 

Intervention:

 

 

 

 

 

 

 

 

 

 

 

2

 

Recruiting

 

SmartCPR Trial: An Analysis of a Waveform-Based AED Algorithm on Survival From Out-of-Hospital Ventricular Fibrillation

 

Conditions:

 

Ventricular Fibrillation;   Cardiac Arrest

 

Interventions:

 

Device: Immediate defibrillation;   Device: SmartCPR;   Other: Delayed defibrillation

 

 

 

 

 

 

 

 

 

3

 

Recruiting

 

A Study of Survivorship Service Capacities Among Health Care Agencies in New York City

 

Condition:

 

All Cancers

 

Intervention:

 

 

 

 

 

 

 

 

 

 

 

4

 

Recruiting

 

Interpersonal Psychotherapy for Depression in Pregnancy

 

Conditions:

 

Major Depression;   Pregnant

 

Intervention:

 

Behavioral: Interpersonal Psychotherapy for Antepartum Depression

 

 

 

 

 

 

 

 

 

5

 

Recruiting

 

Outcome Evaluation of Minority AIDS Initiative Programs in the New York EMA

 

Condition:

 

HIV Infections

 

Interventions:

 

Behavioral: Maintenance in Care Services;   Behavioral: Access to Care Services

 

 

 

 

 

 

 

 

 

6

 

Recruiting

 

Bone Marrow Cell Transplantation to Improve Heart Function in Individuals With End-Stage Heart Failure

 

Condition:

 

Heart Failure, Congestive

 

Interventions:

 

Procedure: Injection of immunoselected CD34+ hematopoietic stem cells;   Procedure: Injection of bone marrow mononuclear cells

 

 

 

 

 

 

 

 

 

7

 

Recruiting

 

Intracerebral Clysis in Treating Patients With Recurrent Primary Brain Tumors

 

Conditions:

 

Recurrent Anaplastic Astrocytoma;   Recurrent Anaplastic Oligodendroglioma;   Recurrent Anaplastic Oligo-Astrocytoma;   Recurrent Glioblastoma Multiforme

 

Interventions:

 

Drug: topotecan;   Procedure: Intracerebral Clysis;   Procedure: MRI

 

 

 

 

 

 

 

 

 

8

 

Recruiting

 

Cardiovascular Disease Risk Factors in Chinese American Immigrants

 

Conditions:

 

Hypertension;   Cardiovascular Diseases;   Diabetes Mellitus;   Metabolic Syndrome X

 

Intervention:

 

 

 

 

 

 

 

 

 

 

 

9

 

Recruiting

 

Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients

 

Conditions:

 

Breast Cancer;   Colon Cancer;   Prostate Cancer

 

Intervention:

 

Genetic: PCR/PCR/LDR Strategy

 

 

 

 

 

 

 

 

 

10

 

Recruiting

 

Treating Depression With Transcranial Direct Current Stimulation (tDCS)

 

Condition:

 

Depression

 

Intervention:

 

Device: ioMed Phoresor (transcranial direct current stimulator)

 

 

 

 

 

 

 

 

 

11

 

Recruiting

 

Intravitreal Ranibizumab Treatment of Central Retinal Vein Occlusion With Macular Edema

 

Condition:

 

Retinal Vein Occlusion

 

Intervention:

 

Drug: Ranibizumab (Lucentis )

 

 

 

 

 

 

 

 

 

12

 

Recruiting

 

Testing the Effectiveness of VOICES as Implemented by STD & HIV Prevention Agencies in the US and PR

 

Condition:

 

Sexually Transmitted Diseases

 

Intervention:

 

Behavioral: VOICES/VOCES

 

 

 

 

 

 

 

 

 

13

 

Recruiting

 

Anti-Psychotic Discontinuation in Alzheimer's Disease

 

Conditions:

 

Alzheimer Disease;   Psychotic Disorders

 

Intervention:

 

Drug: risperidone

 

 

 

 

 

 

 

 

 

14

 

Recruiting

 

HIV Prevention Intervention for Couples

 

Condition:

 

Acquired Immunodeficiency Syndrome

 

Interventions:

 

Behavioral: Couples HIV counseling and testing;   Behavioral: Women's relationship-focused HIV counseling and testing

 

 

 

 

 

 

 

 

 

15

 

Recruiting

 

Double-Blind, Randomized Study Evaluating the Efficacy and Safety of Brivaracetam in Adults With Partial Onset Seizures

 

Condition:

 

Epilepsy

 

Intervention:

 

Drug: Brivaracetam

 

 

 

 

 

 

 

 

 

16

 

Recruiting

 

ZACTIMA (an Anti-EGFR / Anti-VEGF Agent) Combined With Docetaxel Compared to Docetaxel in Non-Small Cell Lung Cancer

 

Conditions:

 

Non-Small Cell Lung Cancer;   Lung Cancer

 

Interventions:

 

Drug: Docetaxel;   Drug: Vandetanib

 

 

 

 

 

 

 

 

 

17

 

Recruiting

 

Fludarabine-Based Conditioning for Severe Aplastic Anemia

 

Condition:

 

Anemia, Aplastic

 

Interventions:

 

Drug: Fludarabine;   Drug: Cyclophosphamide

 

 

 

 

 

 

 

 

 

18

 

Recruiting

 

Pediatric Residency Training On Tobacco

 

Condition:

 

Tobacco Use Disorder

 

Intervention:

 

Behavioral: Pediatric residency training on tobacco

 

 

 

 

 

 

 

 

 

19

 

Recruiting

 

Are Character Building Lessons Effective in Decreasing Bullying Behaviors?

 

Condition:

 

Aggression

 

Intervention:

 

Behavioral: Six classroom based character building education lessons

 

 

 

 

 

 

 

 

 

20

 

Recruiting

 

Collection of Blood for Gene Expression Study in Individuals With Chronic Lung Diseases

 

Condition:

 

Pulmonary Diseases

 

Intervention:

 

 

 

 

 

 

 

 

 

 

 

21

 

Recruiting

 

A Safety Study of an Oral EGFR Inhibitor, AV-412, Administered Three Times Weekly in Advanced Solid Tumor Patients

 

Conditions:

 

Advanced Cancer;   Refractory Cancer

 

Intervention:

 

Drug: AV-412

 

 

 

 

 

 

 

 

 

22

 

Recruiting

 

Paroxetine Versus Bupropion for Treating People With High-Risk Major Depressive Disorder

 

Condition:

 

Depression

 

Interventions:

 

Drug: Paxil CR (paroxetine);   Drug: Wellbutrin XL (bupropion)

 

 

 

 

 

 

 

 

 

23

 

Recruiting

 

Platelet Activation Markers in Pediatric Cardiac Surgery

 

Condition:

 

Coronary Disease

 

Intervention:

 

 

 

 

 

 

 

 

 

 

 

24

 

Recruiting

 

Combined Exposure Therapy and DCS Vs. Placebo for PTSD

 

Condition:

 

Post-Traumatic Stress Disorder

 

Intervention:

 

Drug: D-Cycloserine

 

 

 

 

 

 

 

 

 

25

 

Recruiting

 

Cascade PRFM Study: The Evaluation of Cascade Platelet-Rich Fibrin Matrix (PRFM) on Rotator Cuff Healing

 

Conditions:

 

Rotator Cuff;   Tendon Injuries

 

Intervention:

 

Procedure: Placement of Platelet Rich Fibrin Matrix During Arthroscopic Rotator Cuff Surgery

 

 

 

 

 

 

 

 

 

26

 

Recruiting

 

Acute Myeloid Leukemia T Cell Depletion to Improve Transplants in Adults With Acute Myeloid Leukemia

 

Condition:

 

Leukemia, Myelocytic, Acute

 

Intervention:

 

Procedure: Leukapheresis

 

 

 

 

 

 

 

 

 

27

 

Recruiting

 

Trial to Assess Chelation Therapy (TACT)

 

Condition:

 

Coronary Artery Disease

 

Intervention:

 

Drug: EDTA chelation therapy

 

 

 

 

 

 

 

 

 

28

 

Recruiting

 

Erlotinib or Placebo Following Chemo/RT in Stage III NSCLC.

 

Conditions:

 

Carcinoma, Non-Small-Cell Lung;   Non-Small Cell Lung Cancer;   NSCLC

 

Intervention:

 

Drug: erlotinib (tarceva)

 

 

 

 

 

 

 

 

 

29

 

Recruiting

 

Respimat Combivent Trial in COPD

 

Condition:

 

Pulmonary Disease, Chronic Obstructive

 

Interventions:

 

Drug: Atrovent Respimat (20 mcg) plus placebo COMBIVENT MDI;   Drug: COMBIVENT MDI (36/206 mcg ) plus placebo Combivent Respimat;   Drug: Combivent Respimat (20 mcg/100 mcg) plus placebo COMBIVENT

 

 

 

 

 

 

 

 

 

30

 

Recruiting

 

Targeting INflammation Using SALsalate in Type 2 Diabetes (TINSAL-T2D)

 

Condition:

 

Type 2 Diabetes

 

Interventions:

 

Drug: Salsalate;   Drug: Salsalate

 

 

 

 

 

 

 

 

 

31

 

Recruiting

 

A Trial in Patients With Diffuse Large-B-Cell Lymphoma Comparing Pixantrone Against Doxorubicin

 

Condition:

 

Diffuse Large-Cell Lymphoma

 

Interventions:

 

Drug: CPOP-R;   Drug: CHOP-R

 

 

 

 

 

 

 

 

 

32

 

Recruiting

 

1st or 2nd Line MBC With Previous Avastin Therapy

 

Condition:

 

Breast Cancer

 

Interventions:

 

Drug: Gemcitabine;   Drug: Sorafenib;   Drug: Placebo

 

 

 

 

 

 

 

 

 

33

 

Recruiting

 

A Phase 3 Pivotal Trial Comparing Allovectin-7® Alone vs Chemotherapy Alone in Patients With Stage 3 or Stage 4 Melanoma

 

Condition:

 

Metastatic Melanoma

 

Intervention:

 

Genetic: Allovectin-7®

 

 

 

 

 

 

 

 

 

34

 

Recruiting

 

Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY)

 

Condition:

 

Diabetes Mellitus, Type II

 

Interventions:

 

Drug: Metformin;   Drug: Rosiglitazone;   Behavioral: TODAY Lifestyle Program

 

 

 

 

 

 

 

 

 

35

 

Recruiting

 

Study of Tarceva and Targretin in Stage I-II Lung Cancer

 

Condition:

 

Carcinoma, Non-Small-Cell Lung

 

Intervention:

 

Drug: erlotinib (Tarceva) and bexarotene (Targretin)

 

 

 

 

 

 

 

 

 

36

 

Recruiting

 

A Trial of Pyridoxamine to Lower Urine Oxalate in Subjects With Stone Disease or Hyperoxaluria

 

Condition:

 

Kidney Stones

 

Intervention:

 

Drug: Pyridoxamine

 

 

 

 

 

 

 

 

 

37

 

Recruiting

 

Study of the Trifunctional Antibody Catumaxomab to Treat Recurrent Symptomatic Malignant Ascites

 

Conditions:

 

Ovarian Neoplasms;   Ascites

 

Intervention:

 

Drug: catumaxomab

 

 

 

 

 

 

 

 

 

38

 

Recruiting

 

Study of Tarceva and Targretin Oral Capsules in Patients With Advanced Lung Cancer

 

Condition:

 

Carcinoma, Non-Small-Cell Lung

 

Intervention:

 

Drug: erlotinib and bexarotene

 

 

 

 

 

 

 

 

 

39

 

Recruiting

 

Role of Vascular Endothelial Growth Factor (VEGF) in Acute Lung Injury/Adult Respiratory Distress Syndrome (ARDS)

 

Condition:

 

Respiratory Distress Syndrome, Adult

 

Intervention:

 

 

 

 

 

 

 

 

 

 

 

40

 

Recruiting

 

Study Evaluating ACC-001 in Mild to Moderate Alzheimers Disease Subjects

 

Condition:

 

Alzheimer Disease

 

Interventions:

 

Drug: arm 1-ACC-001 + QS-21-Active;   Drug: ACC-001;   Drug: QS-21-Placebo

 

 

 

 

 

 

 

 

 

41

 

Recruiting

 

Study to Investigate Safety and Effectiveness in Treatment of Insomnia

 

Condition:

 

Insomnia

 

Intervention:

 

Drug: Org 50081

 

 

 

 

 

 

 

 

 

42

 

Recruiting

 

A Phase 1 Study of MDV3100 in Patients With Castration-Resistant (Hormone-Refractory) Prostate Cancer

 

Conditions:

 

Prostate Cancer;   Hormone Refractory Prostate Cancer

 

Intervention:

 

Drug: MDV3100

 

 

 

 

 

 

 

 

 

43

 

Recruiting

 

MIRAGE: Multi-Institutional Research in Alzheimer's Genetic Epidemiology

 

Condition:

 

Alzheimer's Disease

 

Intervention:

 

 

 

 

 

 

 

 

 

 

 

44

 

Recruiting

 

Attention Deficit Hyperactivity Disorder (ADHD) in Adolescents With Substance Use Disorders (SUD)

 

Conditions:

 

ADHD;   Substance Abuse

 

Intervention:

 

Drug: Methylphenidate (OROS-MPH)

 

 

 

 

 

 

 

 

 

45

 

Recruiting

 

Study to Evaluate the Efficacy and Safety of Armodafinil as Treatment for Adults With Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea Syndrome With Comorbid Major Depressive Disorder or Dysthymic Disorder

 

Conditions:

 

Sleep Disorders;   Obstructive Sleep Apnea;   Major Depressive Disorder;   Dysthymic Disorder

 

Interventions:

 

Drug: armodafinil;   Drug: placebo

 

 

 

 

 

 

 

 

 

46

 

Recruiting

 

Gestational Diabetes Mellitus Trial

 

Condition:

 

Diabetes, Gestational

 

Interventions:

 

Behavioral: nutritional counseling;   Behavioral: self blood glucose monitoring

 

 

 

 

 

 

 

 

 

47

 

Recruiting

 

RCT of Progesterone to Prevent Preterm Birth in Nulliparous Women With a Short Cervix

 

Conditions:

 

Preterm Delivery;   Cervical Length

 

Intervention:

 

Drug: 17 alpha-hydroxyprogesterone caproate

 

 

 

 

 

 

 

 

 

48

 

Recruiting

 

A Study of Tanespimycin (KOS-953) in Patients With Relapsed-Refractory Multiple Myeloma

 

Condition:

 

Multiple Myeloma

 

Intervention:

 

Drug: tanespimycin and bortezomib

 

 

 

 

 

 

 

 

 

49

 

Recruiting

 

ESCAPE Migraine Trial

 

Conditions:

 

Migraine Disorders;   Heart Septal Defects, Atrial

 

Intervention:

 

Device: PFO Closure

 

 

 

 

 

 

 

 

 

50

 

Not yet recruiting

 

IL-1 Trap for Treatment of Familial Mediterranean Fever (FMF)

 

Condition:

 

Familial Mediterranean Fever

 

Interventions:

 

Drug: IL1 Trap (Rilonacept);   Drug: Placebo

 

 

 

 

 

 

 

 

 

                             

 

51

 

Recruiting

 

Secondary Prevention of Venous Thrombo Embolism.

Condition:

 

Thromboembolism

Intervention:

 

Drug: warfarin

 

 

 

 

 

 

 

52

 

Recruiting

 

Phase 2 Study of Temozolomide in Pre-Selected Advanced Aerodigestive Tract Cancers (Study P04273)

Conditions:

 

Colorectal Neoplasm;   Head and Neck Neoplasm;   Carcinoma, Non-Small-Cell Lung;   Esophageal Neoplasm

Intervention:

 

Drug: Temozolomide

 

 

 

 

 

 

 

53

 

Recruiting

 

Study of Human Monoclonal Antibody to Treat Mycosis Fungoides and Sezary Syndrome

Conditions:

 

Mycosis Fungoides;   Sezary Syndrome

Intervention:

 

Drug: HuMax-CD4 (zanolimumab)

 

 

 

 

 

 

 

54

 

Not yet recruiting

 

Ph I/II Study of Subcutaneously Administered Veltuzumab (hA20) in NHL and CLL

Conditions:

 

NHL;   Lymphoma, Non-Hodgkin;   Lymphoma, B-Cell;   Lymphoma, Follicular;   Lymphoma, Intermediate-Grade;   Lymphoma, Large-Cell;   Lymphoma, Low-Grade;   Lymphoma, Mixed-Cell;   Lymphoma, Small-Cell;   Leukemia, Lymphocytic, Chronic;   Leukemia, B-Cell, Chronic;   Leukemia, Prolymphocytic;   Leukemia, Small Lymphocytic;   Lymphoma, Small Lymphocytic;   Lymphoma, Lymphoplasmacytoid, CLL;   Lymphoplasmacytoid Lymphoma, CLL;   CLL;   SLL

Intervention:

 

Biological: veltuzumab

 

 

 

 

 

 

 

55

 

Recruiting

 

Phase II Study in Patients With Operable Breast Cancer

Condition:

 

Breast Cancer

Intervention:

 

Drug: Pegylated Liposomal Doxorubicin

 

 

 

 

 

 

 

56

 

Recruiting

 

A Study of Acyclovir to Help Prevent HIV Infection in People With Genital Herpes

Conditions:

 

HIV Infections;   HIV Seronegativity;   Herpes Genitalis

Intervention:

 

Drug: Acyclovir

 

 

 

 

 

 

 

57

 

Recruiting

 

SUPARTZ Versus Placebo in Osteoarthritis of the Shoulder

Condition:

 

Glenohumeral Osteoarthritis of the Shoulder

Intervention:

 

Device: SUPARTZ

 

 

 

 

 

 

 

58

 

Recruiting

 

Comparing Cognitive Behavioral Therapy, Antidepressant Medication, and Combined Treatment in Individuals With Hypochondriasis

Condition:

 

Hypochondriasis

Interventions:

 

Drug: Fluoxetine;   Behavioral: Cognitive Behavioral Therapy;   Other: Supportive Therapy;   Drug: Placebo

 

 

 

 

 

 

 

59

 

Recruiting

 

Predictors of Cognitive Decline in Normal Aging

Conditions:

 

Alzheimer Disease;   Dementia

Intervention:

 

 

 

 

 

 

 

 

 

60

 

Recruiting

 

Biliary Atresia Research Consortium

Conditions:

 

Biliary Atresia;   Cholestasis

Intervention:

 

 

 

 

 

 

 

 

 

61

 

Recruiting

 

Stimulant Versus Nonstimulant Medication for Attention Deficit Hyperactivity Disorder in Children

Condition:

 

Attention Deficit Disorder With Hyperactivity

Interventions:

 

Drug: Atomoxetine;   Drug: Methylphenidate

 

 

 

 

 

 

 

62

 

Recruiting

 

Normal Lung Collection: Evaluation of the Lungs of Normal Individuals With Segmental Bronchopulmonary Lung Lavage, Bronchial Brushing, and Bronchial Wall Biopsy

Condition:

 

Lung Diseases

Intervention:

 

 

 

 

 

 

 

 

 

63

 

Recruiting

 

Anti-Pseudomonas Immune Status and Dendritic Cell Preparation in Normal Individuals

Condition:

 

Normal Volunteers

Intervention:

 

 

 

 

 

 

 

 

 

64

 

Recruiting

 

The Effects of Alendronate After Cure of Primary Hyperparathyroidism

Condition:

 

Hyperparathyroidism

Intervention:

 

Drug: Alendronate

 

 

 

 

 

 

 

65

 

Recruiting

 

Varenicline Effects In Schizophrenic Smokers

Conditions:

 

Schizophrenia;   Tobocco Use Disorder;   Nicotine Dependance

Intervention:

 

Drug: Varenicline

 

 

 

 

 

 

 

66

 

Recruiting

 

CT-322 in Treating Patients With Recurrent Glioblastoma Multiforme and Combination Therapy With Irinotecan

Condition:

 

Brain and Central Nervous System Tumors

Interventions:

 

Drug: CT-322, antiangiogenesis therapy;   Drug: irinotecan hydrochloride

 

 

 

 

 

 

 

67

 

Recruiting

 

Evaluating the Genetic Causes and Progression of Cholestatic Liver Diseases

Conditions:

 

Liver Diseases;   Alagille Syndrome;   Alpha 1-Antitrypsin Deficiency

Intervention:

 

 

 

 

 

 

 

 

 

68

 

Recruiting

 

Positive Exposure: A Photography and Video Intervention for Individuals With Craniofacial Differences

Condition:

 

Craniofacial Differences

Intervention:

 

 

 

 

 

 

 

 

 

69

 

Recruiting

 

Study of the Clinical Effectiveness of a Human Monoclonal Antibody to C. Difficile Toxin A and Toxin B in Patients With Clostridium Difficile Associated Disease

Condition:

 

Clostridium Infections

Interventions:

 

Biological: GS-CDA1;   Biological: MDX-1388;   Biological: normal saline

 

 

 

 

 

 

 

70

 

Recruiting

 

Inner-City Anti-IgE Therapy for Asthma

Condition:

 

Asthma

Interventions:

 

Drug: Omalizumab;   Biological: Standardized asthma care

 

 

 

 

 

 

 

71

 

Recruiting

 

RED-HF™ Trial - Reduction of Events With Darbepoetin Alfa in Heart Failure Trial

Conditions:

 

Heart Failure;   Anemia;   Cardiovascular Disease;   Ventricular Dysfunction;   Congestive Heart Failure

Intervention:

 

Drug: Darbepoetin alfa

 

 

 

 

 

 

 

72

 

Recruiting

 

Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)

Condition:

 

Breast Cancer

Interventions:

 

Drug: anastrozole;   Drug: exemestane;   Drug: letrozole;   Drug: tamoxifen citrate;   Procedure: adjuvant therapy;   Procedure: antiestrogen therapy;   Procedure: aromatase inhibition therapy;   Procedure: chemotherapy;   Procedure: cytogenetic analysis;   Procedure: diagnostic procedure;   Procedure: laboratory biomarker analysis;   Procedure: radiation therapy

 

 

 

 

 

 

 

73

 

Recruiting

 

ICATA Asthma Mechanistic Study

Condition:

 

Asthma

Intervention:

 

 

 

 

 

 

 

 

 

74

 

Recruiting

 

Sunitinib or Sorafenib in Treating Patients With Kidney Cancer That Was Removed By Surgery

Condition:

 

Kidney Cancer

Interventions:

 

Drug: sorafenib tosylate;   Drug: sunitinib malate;   Procedure: adjuvant therapy;   Procedure: antiangiogenesis therapy;   Procedure: conventional surgery;   Procedure: diagnostic procedure;   Procedure: enzyme inhibitor therapy;   Procedure: laboratory biomarker analysis;   Procedure: protein tyrosine kinase inhibitor therapy

 

 

 

 

 

 

 

75

 

Recruiting

 

International Immune Tolerance Study

Condition:

 

Hemophilia A With Inhibitors

Intervention:

 

Drug: Factor VIII concentrates

 

 

 

 

 

 

 

76

 

Recruiting

 

Docetaxel and Prednisone With or Without Bevacizumab in Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy

Condition:

 

Prostate Cancer

Interventions:

 

Drug: bevacizumab;   Drug: docetaxel;   Drug: prednisone;   Procedure: antiangiogenesis therapy;   Procedure: chemotherapy;   Procedure: monoclonal antibody therapy

 

 

 

 

 

 

 

77

 

Recruiting

 

Zoledronate, Clodronate, or Ibandronate in Treating Women Who Have Undergone Surgery for Stage I, Stage II, or Stage III Breast Cancer

Condition:

 

Breast Cancer

Interventions:

 

Drug: clodronate disodium;   Drug: ibandronate sodium;   Drug: zoledronic acid;   Procedure: adjuvant therapy;   Procedure: bone metastases prevention

 

 

 

 

 

 

 

78

 

Recruiting

 

Adjuvant Doxorubicin, Cyclophosphamide, and Paclitaxel in Treating Patients With Breast Cancer

Condition:

 

Breast Cancer

Interventions:

 

Drug: cyclophosphamide;   Drug: doxorubicin hydrochloride;   Drug: filgrastim;   Drug: paclitaxel;   Drug: pegfilgrastim;   Drug: trastuzumab;   Procedure: adjuvant therapy;   Procedure: chemotherapy;   Procedure: colony-stimulating factor therapy;   Procedure: monoclonal antibody therapy

 

 

 

 

 

 

 

79

 

Recruiting

 

Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia

Condition:

 

Leukemia

Interventions:

 

Drug: cyclophosphamide;   Drug: cytarabine;   Drug: daunorubicin hydrochloride;   Drug: dexamethasone;   Drug: doxorubicin hydrochloride;   Drug: leucovorin calcium;   Drug: mercaptopurine;   Drug: methotrexate;   Drug: pegaspargase;   Drug: prednisone;   Drug: thioguanine;   Drug: vincristine;   Procedure: chemotherapy;   Procedure: high-dose chemotherapy;   Procedure: radiation therapy

 

 

 

 

 

 

 

80

 

Recruiting

 

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Condition:

 

Leukemia

Interventions:

 

Drug: cyclophosphamide;   Drug: cytarabine;   Drug: daunorubicin hydrochloride;   Drug: dexamethasone;   Drug: doxorubicin hydrochloride;   Drug: leucovorin calcium;   Drug: mercaptopurine;   Drug: methotrexate;   Drug: pegaspargase;   Drug: thioguanine;   Drug: vincristine;   Procedure: chemotherapy;   Procedure: intrathecal chemotherapy;   Procedure: radiation therapy;   Procedure: steroid therapy

 

 

 

 

 

 

 

81

 

Recruiting

 

Risk-Group Classification of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Condition:

 

Leukemia

Interventions:

 

Procedure: DNA ploidy analysis;   Procedure: biopsy;   Procedure: chromosomal translocation analysis;   Procedure: diagnostic procedure;   Procedure: fluorescence in situ hybridization;   Procedure: immunologic technique;   Procedure: laboratory biomarker analysis;   Procedure: molecular genetic technique;   Procedure: polymorphism analysis

 

 

 

 

 

 

 

82

 

Recruiting

 

Combination Chemotherapy With or Without Gemtuzumab in Treating Young Patients With Newly Diagnosed Acute Myeloid Leukemia

Condition:

 

Leukemia

Interventions:

 

Drug: anti-thymocyte globulin;   Drug: asparaginase;   Drug: busulfan;   Drug: cyclophosphamide;   Drug: cyclosporine;   Drug: cytarabine;   Drug: daunorubicin hydrochloride;   Drug: etoposide;   Drug: gemtuzumab ozogamicin;   Drug: methotrexate;   Drug: mitoxantrone hydrochloride;   Procedure: allogeneic bone marrow transplantation;   Procedure: allogeneic hematopoietic stem cell transplantation;   Procedure: chemotherapy;   Procedure: graft versus host disease prophylaxis/therapy;   Procedure: high-dose chemotherapy;   Procedure: immunoglobulin therapy;   Procedure: intrathecal chemotherapy;   Procedure: monoclonal antibody therapy;   Procedure: umbilical cord blood transplantation

 

 

 

 

 

 

 

83

 

Recruiting

 

Epratuzumab and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia

Condition:

 

Leukemia

Interventions:

 

Drug: asparaginase;   Drug: cyclophosphamide;   Drug: cytarabine;   Drug: doxorubicin hydrochloride;   Drug: epratuzumab;   Drug: etoposide;   Drug: filgrastim;   Drug: leucovorin calcium;   Drug: methotrexate;   Drug: pegaspargase;   Drug: prednisone;   Drug: therapeutic hydrocortisone;   Drug: vincristine;   Procedure: chemotherapy;   Procedure: colony-stimulating factor therapy;   Procedure: high-dose chemotherapy;   Procedure: monoclonal antibody therapy

 

 

 

 

 

 

 

84

 

Recruiting

 

Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)

Conditions:

 

Systemic Lupus Erythematosus;   Antiphospholipid Syndrome

Intervention:

 

 

 

 

 

 

 

 

 

85

 

Recruiting

 

Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary CNS Germ Cell Tumor

Condition:

 

Brain and Central Nervous System Tumors

Interventions:

 

Drug: carboplatin;   Drug: cisplatin;   Drug: cyclophosphamide;   Drug: etoposide;   Drug: filgrastim;   Procedure: chemotherapy;   Procedure: colony-stimulating factor therapy;   Procedure: radiation therapy

 

 

 

 

 

 

 

86

 

Recruiting

 

Treatment for Acute Graft-Versus-Host Disease

Conditions:

 

Graft vs Host Disease;   Immune System Disorders

Interventions:

 

Drug: Etanercept;   Drug: Mycophenolate Mofeil;   Drug: Denileukin Diftitok;   Drug: Pentostatin

 

 

 

 

 

 

 

87

 

Recruiting

 

Carboplatin, Paclitaxel, and Pegfilgrastim in Treating Patients With Stage III or Stage IV Ovarian Epithelial, Fallopian Tube, Primary Peritoneal, or Carcinosarcoma Cancer

Conditions:

 

Fallopian Tube Cancer;   Infection;   Neutropenia;   Ovarian Cancer;   Peritoneal Cavity Cancer

Interventions:

 

Drug: carboplatin;   Drug: paclitaxel;   Drug: pegfilgrastim;   Procedure: adjuvant therapy;   Procedure: chemotherapy;   Procedure: colony-stimulating factor therapy;   Procedure: complications of therapy management;   Procedure: hematologic toxicity attenuation;   Procedure: infection prophylaxis and management

 

 

 

 

 

 

 

88

 

Recruiting

 

Comparing Peripheral Blood Stem Cell Transplantation Versus Bone Marrow Transplantation in Individuals With Hematologic Cancers

Conditions:

 

Acute Leukemia;   Chronic Leukemia;   Chronic Myeloproliferative Disorders;   Myelodysplastic and Myeloproliferative Disease

Interventions:

 

Procedure: allogeneic bone marrow transplantation;   Procedure: peripheral blood stem cell transplantation

 

 

 

 

 

 

 

89

 

Recruiting

 

Comparison of Combination Chemotherapy Regimens With or Without Cetuximab in Treating Patients Who Have Undergone Surgery For Stage III Colon Cancer

Condition:

 

Colorectal Cancer

Interventions:

 

Drug: cetuximab;   Drug: fluorouracil;   Drug: irinotecan hydrochloride;   Drug: leucovorin calcium;   Drug: oxaliplatin;   Procedure: adjuvant therapy;   Procedure: chemotherapy;   Procedure: monoclonal antibody therapy

 

 

 

 

 

 

 

90

 

Recruiting

 

Comparison of Two Combination Chemotherapy Regimens in Treating Women With Breast Cancer

Condition:

 

Breast Cancer

Interventions:

 

Drug: cyclophosphamide;   Drug: doxorubicin hydrochloride;   Drug: epirubicin hydrochloride;   Drug: fluorouracil;   Procedure: adjuvant therapy;   Procedure: chemotherapy;   Procedure: radiation therapy

 

 

 

 

 

 

 

91

 

Recruiting

 

Letrozole in Treating Postmenopausal Women Who Have Received Hormone Therapy for Hormone Receptor-Positive Breast Cancer

Condition:

 

Breast Cancer

Interventions:

 

Drug: letrozole;   Procedure: aromatase inhibition therapy

 

 

 

 

 

 

 

92

 

Recruiting

 

Radiation Therapy in Treating Women Who Have Undergone Surgery For Ductal Carcinoma In Situ or Stage I or Stage II Breast Cancer

Condition:

 

Breast Cancer

Interventions:

 

Procedure: adjuvant therapy;   Procedure: radiation therapy

 

 

 

 

 

 

 

93

 

Recruiting

 

Oxaliplatin, Leucovorin, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer

Condition:

 

Colorectal Cancer

Interventions:

 

Drug: bevacizumab;   Drug: fluorouracil;   Drug: leucovorin calcium;   Drug: oxaliplatin;   Procedure: adjuvant therapy;   Procedure: antiangiogenesis therapy;   Procedure: chemotherapy;   Procedure: monoclonal antibody therapy

 

 

 

 

 

 

 

94

 

Recruiting

 

Carboplatin and Paclitaxel With or Without Sorafenib in Treating Patients With Unresectable Stage III or Stage IV Melanoma

Condition:

 

Melanoma (Skin)

Interventions:

 

Drug: carboplatin;   Drug: paclitaxel;   Drug: sorafenib tosylate;   Procedure: antiangiogenesis therapy;   Procedure: chemotherapy;   Procedure: enzyme inhibitor therapy

 

 

 

 

 

 

 

95

 

Recruiting

 

Intensity-Modulated Radiation Therapy to the Pelvis With or Without Chemotherapy in Treating Patients With Endometrial Cancer or Cervical Cancer That Has Been Removed By Surgery

Conditions:

 

Cervical Cancer;   Endometrial Cancer

Interventions:

 

Drug: cisplatin;   Procedure: chemotherapy;   Procedure: intensity-modulated radiation therapy

 

 

 

 

 

 

 

96

 

Recruiting

 

Single-Fraction Radiation Therapy Compared With Multiple-Fraction Reirradiation Therapy in Treating Patients With Painful Bone Metastases

Conditions:

 

Metastatic Cancer;   Pain

Interventions:

 

Procedure: pain therapy;   Procedure: radiation therapy

 

 

 

 

 

 

 

97

 

Recruiting

 

Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

Condition:

 

Brain and Central Nervous System Tumors

Interventions:

 

Drug: temozolomide;   Procedure: adjuvant therapy;   Procedure: chemotherapy;   Procedure: radiation therapy

 

 

 

 

 

 

 

98

 

Recruiting

 

Radiation Therapy and Cisplatin With or Without Cetuximab in Treating Patients With Stage III or Stage IV Head and Neck Cancer

Condition:

 

Head and Neck Cancer

Interventions:

 

Drug: cetuximab;   Drug: cisplatin;   Procedure: chemotherapy;   Procedure: conventional surgery;   Procedure: monoclonal antibody therapy;   Procedure: radiation therapy;   Procedure: radiosensitization

 

 

 

 

 

 

 

99

 

Recruiting

 

Intensity-Modulated Radiation Therapy, Fluorouracil, and Mitomycin C in Treating Patients With Invasive Anal Cancer

Condition:

 

Anal Cancer

Interventions:

 

Drug: fluorouracil;   Drug: mitomycin C;   Procedure: chemotherapy;   Procedure: intensity-modulated radiation therapy

 

 

 

 

 

 

 

100

 

Recruiting

 

Single Versus Double Umbilical Cord Blood Transplantation in Children With High Risk Leukemia and Myelodysplasia

Conditions:

 

Acute Myelogenous Leukemia;   Acute Lymphocytic Leukemia;   Chronic Myelogenous Leukemia;   Myelodysplastic Syndrome

Interventions:

 

Drug: Fludarabine;   Drug: Total Body Irradiation (TBI);   Drug: Cyclophosphamide;   Drug: Mycophenolate Mofetil (MMF);   Drug: Cyclosporine A (CSA)

 

 

 

 

 

 

 

151

 

Recruiting

 

Bortezomib With or Without Irinotecan in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

 

Condition:

 

Head and Neck Cancer

 

Interventions:

 

Drug: bortezomib;   Drug: irinotecan hydrochloride;   Procedure: chemotherapy;   Procedure: enzyme inhibitor therapy

 

 

 

 

 

 

 

 

 

152

 

Recruiting

 

Bortezomib in Treating Patients With Advanced Cancer and Kidney Dysfunction

 

Conditions:

 

Lymphoma;   Multiple Myeloma and Plasma Cell Neoplasm;   Unspecified Adult Solid Tumor, Protocol Specific

 

Interventions:

 

Drug: bortezomib;   Procedure: enzyme inhibitor therapy

 

 

 

 

 

 

 

 

 

153

 

Recruiting

 

Lenalidomide in Treating Patients Who Are Undergoing Autologous Stem Cell Transplant for Multiple Myeloma

 

Condition:

 

Multiple Myeloma and Plasma Cell Neoplasm

 

Interventions:

 

Drug: cyclophosphamide;   Drug: filgrastim;   Drug: lenalidomide;   Drug: melphalan;   Procedure: chemotherapy;   Procedure: colony-stimulating factor therapy;   Procedure: high-dose chemotherapy;   Procedure: non-specific immune-modulator therapy;   Procedure: peripheral blood stem cell transplantation

 

 

 

 

 

 

 

 

 

154

 

Recruiting

 

Temozolomide and Radiation Therapy in Treating Patients With Gliomas

 

Condition:

 

Brain and Central Nervous System Tumors

 

Interventions:

 

Drug: temozolomide;   Procedure: adjuvant therapy;   Procedure: chemotherapy;   Procedure: radiation therapy

 

 

 

 

 

 

 

 

 

155

 

Recruiting

 

Exemestane in Preventing Cancer in Postmenopausal Women at Increased Risk of Developing Breast Cancer

 

Condition:

 

Breast Cancer

 

Interventions:

 

Drug: exemestane;   Procedure: aromatase inhibition therapy;   Procedure: chemoprevention

 

 

 

 

 

 

 

 

 

156

 

Recruiting

 

A Study of Belimumab in Subjects With Systemic Lupus Erythematosus (SLE)

 

Condition:

 

Systemic Lupus Erythematosus

 

Interventions:

 

Drug: belimumab;   Drug: Placebo

 

 

 

 

 

 

 

 

 

157

 

Recruiting

 

Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST)

 

Conditions:

 

Stroke;   Cerebral Infarction;   Carotid Stenosis;   Atherosclerosis

 

Interventions:

 

Procedure: carotid endarterectomy;   Procedure: carotid angioplasty with stenting

 

 

 

 

 

 

 

 

 

158

 

Recruiting

 

Selenium in Preventing Tumor Growth in Patients With Previously Resected Stage I Non-Small Cell Lung Cancer

 

Condition:

 

Lung Cancer

 

Interventions:

 

Drug: selenium;   Procedure: chemoprevention;   Procedure: preventative nutritional supplementation

 

 

 

 

 

 

 

 

 

159

 

Recruiting

 

Comparison of Two Salvage Chemotherapy Regimens Before Autologous Stem Cell Transplantation With or Without Maintenance Rituximab in Treating Patients With Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma

 

Condition:

 

Lymphoma

 

Interventions:

 

Drug: cisplatin;   Drug: cytarabine;   Drug: dexamethasone;   Drug: gemcitabine hydrochloride;   Drug: rituximab;   Procedure: autologous bone marrow transplantation;   Procedure: chemotherapy;   Procedure: high-dose chemotherapy;   Procedure: monoclonal antibody therapy;   Procedure: peripheral blood stem cell transplantation

 

 

 

 

 

 

 

 

 

160

 

Recruiting

 

Rosiglitazone (Extended Release Tablets) As Adjunctive Therapy In Subjects With Mild To Moderate Alzheimer's Disease

 

Condition:

 

Alzheimer's Disease

 

Intervention:

 

Drug: Rosiglitazone XR (extended release) oral tablets

 

 

 

 

 

 

 

 

 

161

 

Recruiting

 

Irinotecan and Temozolomide in Treating Young Patients With Recurrent Neuroblastoma

 

Condition:

 

Neuroblastoma

 

Interventions:

 

Drug: irinotecan hydrochloride;   Drug: temozolomide;   Procedure: chemotherapy

 

 

 

 

 

 

 

 

 

162

 

Recruiting

 

A Comparison of AZD6140 and Clopidogrel in Patients With Acute Coronary Syndrome

 

Condition:

 

Acute Coronary Syndrome

 

Interventions:

 

Drug: AZD6140;   Drug: Clopidogrel

 

 

 

 

 

 

 

 

 

163

 

Recruiting

 

Natural History Study of Infants With Adrenal Masses Found on Prenatal and/or Neonatal Imaging

 

Conditions:

 

Adrenocortical Carcinoma;   Neuroblastoma;   Precancerous/Nonmalignant Condition

 

Interventions:

 

Procedure: computed tomography;   Procedure: diagnostic procedure;   Procedure: magnetic resonance imaging

 

 

 

 

 

 

 

 

 

164

 

Recruiting

 

Letrozole After Tamoxifen in Treating Women With Breast Cancer

 

Condition:

 

Breast Cancer

 

Interventions:

 

Drug: letrozole;   Procedure: aromatase inhibition therapy

 

 

 

 

 

 

 

 

 

165

 

Recruiting

 

Cisplatin and Radiation Therapy With or Without Tirapazamine in Treating Patients With Cervical Cancer

 

Condition:

 

Cervical Cancer

 

Interventions:

 

Drug: cisplatin;   Drug: tirapazamine;   Procedure: chemosensitization/potentiation therapy;   Procedure: chemotherapy;   Procedure: radiation brachytherapy;   Procedure: radiation therapy;   Procedure: radiosensitization

 

 

 

 

 

 

 

 

 

166

 

Recruiting

 

Anastrozole With or Without Fulvestrant as First-Line Therapy in Treating Postmenopausal Women With Metastatic Breast Cancer

 

Condition:

 

Breast Cancer

 

Interventions:

 

Drug: anastrozole;   Drug: fulvestrant;   Procedure: antiestrogen therapy;   Procedure: aromatase inhibition therapy

 

 

 

 

 

 

 

 

 

167

 

Recruiting

 

Rosiglitazone (Extended Release Tablets) Monotherapy In Subjects With Mild To Moderate Alzheimer's Disease

 

Condition:

 

Alzheimer's Disease

 

Intervention:

 

Drug: Rosiglitazone XR (extended release) oral tablets

 

 

 

 

 

 

 

 

 

168

 

Recruiting

 

Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors

 

Conditions:

 

Childhood Germ Cell Tumor;   Extragonadal Germ Cell Tumor;   Ovarian Cancer

 

Interventions:

 

Drug: bleomycin;   Drug: cisplatin;   Drug: etoposide;   Procedure: chemotherapy;   Procedure: conventional surgery

 

 

 

 

 

 

 

 

 

169

 

Recruiting

 

Safety and Effectiveness of 3 Doses of Crofelemer Compared to Placebo in the Treatment of HIV Associated Diarrhea

 

Conditions: